國立清華大學腦科學研究中心

基因與疾病

Hui-Yun Chang / 張慧雲

Job Title 清華大學 生物科技研究所 副教授
Highest Degree 美國普度大學博士
Professional Memberships
  • 2010-present Neuroscience Society of Taiwan.
  • 2006-present Member, Genetics Society of America.
  • 2004-present Member, Society for Neuroscience.
Experience
  • 2011-present Associate Professor, Institute of Biotechnology, National Tsing Hua University, Taiwan
  • 2006-2011 Assistant Professor, Institute of Biotechnology, National Tsing Hua University, Taiwan
  • 2005-2006 Research Associate, Department of Neurology, University of California, Los Angeles, USA
Publication List
  • Chuang CL, Lu YN, Wang HC, Chang HY. (2014) Genetic dissection reveals that Akt is the critical kinase downstream of LRRK2 to phosphorylate and inhibit FOXO1, and promotes neuron survival. Hum Mol Genet. 2014 Nov 1;23(21):5649-58. Link
  • Wu TH, Lu YN, Chuang CL, Wu CL, Chiang AS, Krantz DE, Chang HY. (2013) Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau. Acta Neuropathol. 2013 May;125(5):711-25. Link
  • Lawal HO, Chang HY, Terrell AN, Brooks ES, Pulido D, Simon AF, Krantz DE. (2010) The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons. Neurobiol Dis. 2010 May 13. [Epub ahead of print] Link
  • Simon AF, Daniels R, Romero-Calderón R, Grygoruk A, Chang HY, Najibi R, Shamouelian D, Salazar E, Solomon M, Ackerson LC, Maidment NT, Diantonio A, Krantz DE. (2009) Drosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin. Genetics. 181:525-41. Link
  • Sang TK, Chang HY, Lawless GM, Ratnaparkhi A, Mee L, Ackerson LC, Maidment NT, Krantz DE, Jackson GR. (2007) A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J Neurosci. Jan 31;27(5):981-92. (co-first author) Link
Email huiyun@life.nthu.edu.tw
Link http://life.nthu.edu.tw/~labhuiyun/wbepage/Leader.html