Brain Research Center at National Tsing Hua University

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Novel Optical Microscopies to Unravel Brain Function

2020 /06

Brain function stems from emergent properties of interconnected neuron networks, which requires in vivo volumetric imaging with high spatial/temporal resolution. Here, we introduce our recent technical developments for Drosophila brain imaging.
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Research Focus

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FlyCircuit is the world's first 3D single neuron image database. It is a public database for online archiving, cell type inventory, browsing, searching and 3D visualization of individual neurons in the Drosophila brain.

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Memory is one of the core functions of the brain. The memory group of Brain Research Center at NTHU is utilizing Drosophila as the animal model to investigate the mechanism of memory formation.

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The members of the Gene and Disease group aim to utilize comprehensive connectome data obtained in the BRC to delineate the functional map of the brain that involves memory and brain disorder.

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We have developed an powerful approach using integrated synchrotron X-ray tomography techniques for fast three dimensional (3D) imaging of a large population of individual neurons in animal brains without tissue clearing or physical sectioning.

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As the number of neuronal images in the Brain Research Center’s database increases dramatically, two fundamental questions need to be answered.

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The construction of three-dimensional brain neural network structure and functional maps requires a variety of core technologies.

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人腦是全身上下最複雜的組織,使用全身80%能量來處理我們每天的工作。MRI,FMRI與EEG的問世,讓我們有機會一窺腦中結構與活動的奧秘。

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教育的目標是以最有效的方式提升人腦的功能與效率。近年來腦科學快速進展,許多新的腦知識與次世代人才培育息息相關,歐美各國紛紛訂定腦意識週(Brain Awareness Week)提倡全民腦意識教學計劃。

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